Selected Publications


Vassoler, F. M., Isgate, S. B., Budge, K. E., & Byrnes, E. M. (2022). HPA Axis Dysfunction during Morphine Withdrawal in Offspring of Female Rats Exposed to Opioids Preconception. Neuroscience Letters, 136479.

Toorie, A. M., Vassoler, F. M., Qu, F., Slonim, D., Schonhoff, C. M., & Byrnes, E. M. (2022). Intergenerational effects of preconception opioids on glucose homeostasis and hepatic transcription in adult male rats. Scientific reports12(1), 1-12.


Vassoler, F. M., & Wimmer, M. E. (2021). Consequences of parental opioid exposure on neurophysiology, behavior, and health in the next generations. Cold Spring Harbor Perspectives in Medicine11(10), a040436.

Mair, L. O., Adam, G., Chowdhury, S., Davis, A., Arifin, D. R., Vassoler, F. M., … & Cappelleri, D. J. (2021). Soft Capsule Magnetic Millirobots for Region-Specific Drug Delivery in the Central Nervous System. Frontiers in Robotics and AI, 226.

Vassoler, F. M., & Byrnes, E. M. (2021). Transgenerational effects on anxiety-like behavior following adolescent morphine exposure in female rats. Behavioural Brain Research406, 113239.

Kumar, M., Rainville, J. R., Williams, K., Lile, J. A., Hodes, G. E., Vassoler, F. M., & Turner, J. R. (2021). Sexually dimorphic neuroimmune response to chronic opioid treatment and withdrawal. Neuropharmacology186, 108469.

Toorie, A. M., Vassoler, F. M., Qu, F., Schonhoff, C. M., Bradburn, S., Murgatroyd, C. A., … & Byrnes, E. M. (2021). A history of opioid exposure in females increases the risk of metabolic disorders in their future male offspring. Addiction biology26(1), e12856.


Guercio, L. A., Wimmer, M. E., Schmidt, H. D., Swinford-Jackson, S. E., Pierce, R. C., & Vassoler, F. M. (2020). Deep brain stimulation of the infralimbic cortex attenuates cocaine priming-induced reinstatement of drug seeking. Brain research1746, 147011.

Wlodarczyk-Li, S. A., Vassoler, F. M., Byrnes, E. M., & Schonhoff, C. M. (2020). Oxycodone decreases dendritic complexity in female but not male rat striatal neurons in vitro. Neuroscience Letters722, 134856.

Vassoler, F. M., Toorie, A. M., Teceno, D. N., Walia, P., Moore, D. J., Patton, T. D., & Byrnes, E. M. (2020). Paternal morphine exposure induces bidirectional effects on cocaine versus opioid self-administration. Neuropharmacology162, 107852.


Vassoler, F. M., Toorie, A. M., & Byrnes, E. M. (2019). Multi-, inter-, and transgenerational effects of drugs of abuse on behavior. Behavioral Neurogenomics, 247-258.

Lambert, K. G., & Byrnes, E. M. (2019). Challenges to the parental brain: Neuroethological and translational considerations. Frontiers in Neuroendocrinology53, 100747.

Mair, L. O., Weinberg, I. N., Teceno, D. N., Jafari, S., Sun, D., Stepanov, P., … & Vassoler, F. M. (2019, March). Rat behavioral changes due to implanted magnetic particles activated with externally-applied magnetic fields. In 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) (pp. 977-980). IEEE.

Wimmer, M. E., Vassoler, F. M., White, S. L., Schmidt, H. D., Sidoli, S., Han, Y., … & Pierce, R. C. (2019). Impaired cocaine‐induced behavioral plasticity in the male offspring of cocaine‐experienced sires. European Journal of Neuroscience49(9), 1115-1126.

Vassoler, F. M., Toorie, A. M., & Byrnes, E. M. (2019). Increased cocaine reward in offspring of females exposed to morphine during adolescence. Psychopharmacology236(4), 1261-1272.


Byrnes, E. M., & Vassoler, F. M. (2018). Modeling prenatal opioid exposure in animals: current findings and future directions. Frontiers in neuroendocrinology51, 1-13.

Vassoler, F. M., Oranges, M. L., Toorie, A. M., & Byrnes, E. M. (2018). Oxycodone self-administration during pregnancy disrupts the maternal-infant dyad and decreases midbrain OPRM1 expression during early postnatal development in rats. Pharmacology Biochemistry and Behavior173, 74-83.

Mueller, M., Byrnes, E., Buczek, D., Linder, D., Freeman, L., & Webster, C. (2018). Engagement in science and engineering through animal-based curricula. Journal of STEM Education18(5).

Vassoler, F. M., Toorie, A. M., & Byrnes, E. M. (2018). Transgenerational blunting of morphine-induced corticosterone secretion is associated with dysregulated gene expression in male offspring. Brain research1679, 19-25.


Vassoler, F. M., Oliver, D. J., Wyse, C., Blau, A., Shtutman, M., Turner, J. R., & Byrnes, E. M. (2017). Transgenerational attenuation of opioid self-administration as a consequence of adolescent morphine exposure. Neuropharmacology113, 271-280.


Bless, E. P., Yang, J., Acharya, K. D., Nettles, S. A., Vassoler, F. M., Byrnes, E. M., & Tetel, M. J. (2016). Adult neurogenesis in the female mouse hypothalamus: estradiol and high-fat diet alter the generation of newborn neurons expressing estrogen receptor α. Eneuro3(4).

Bodi, C. M., Vassoler, F. M., & Byrnes, E. M. (2016). Adolescent experience affects postnatal ultrasonic vocalizations and gene expression in future offspring. Developmental psychobiology58(6), 714-723.

Vassoler, F. M., Wright, S. J., & Byrnes, E. M. (2016). Exposure to opiates in female adolescents alters mu opiate receptor expression and increases the rewarding effects of morphine in future offspring. Neuropharmacology103, 112-121.

White, S. L., Vassoler, F. M., Schmidt, H. D., Pierce, R. C., & Wimmer, M. E. (2016). Enhanced anxiety in the male offspring of sires that self‐administered cocaine. Addiction biology21(4), 802-810.


Meadows, K. L., & Byrnes, E. M. (2015). Sex-and age-specific differences in relaxin family peptide receptor expression within the hippocampus and amygdala in rats. Neuroscience284, 337-348.


Ravenelle, R., Santolucito, H. B., Byrnes, E. M., Byrnes, J. J., & Donaldson, S. T. (2014). Housing environment modulates physiological and behavioral responses to anxiogenic stimuli in trait anxiety male rats. Neuroscience270, 76-87.

Vassoler, F. M., Johnson-Collins, N. L., Carini, L. M., & Byrnes, E. M. (2014). Next generation effects of female adolescent morphine exposure: sex-specific alterations in response to acute morphine emerge before puberty. Behavioural pharmacology25(2), 173.

Vassoler, F. M., & Sadri-Vakili, G. (2014). Mechanisms of transgenerational inheritance of addictive-like behaviors. Neuroscience264, 198-206.

Akay, C., Cooper, M., Odeleye, A., Jensen, B. K., White, M. G., Vassoler, F., … & Jordan-Sciutto, K. L. (2014). Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system. Journal of neurovirology20(1), 39-53.

Vassoler, F. M., Byrnes, E. M., & Pierce, R. C. (2014). The impact of exposure to addictive drugs on future generations: Physiological and behavioral effects. Neuropharmacology76, 269-275.


Byrnes, E. M., Casey, K., Carini, L. M., & Bridges, R. S. (2013). Reproductive experience alters neural and behavioural responses to acute oestrogen receptor α activation. Journal of neuroendocrinology25(12), 1280-1289.

Vassoler, F. M., Johnson, N. L., & Byrnes, E. M. (2013). Female adolescent exposure to cannabinoids causes transgenerational effects on morphine sensitization in female offspring in the absence of in utero exposure. Journal of psychopharmacology27(11), 1015-1022.

Ravenelle, R., Byrnes, E. M., Byrnes, J. J., McInnis, C., Park, J. H., & Donaldson, S. T. (2013). Environmental enrichment effects on the neurobehavioral profile of selective outbred trait anxiety rats. Behavioural brain research252, 49-57.

Byrnes, J. J., Johnson, N. L., Carini, L. M., & Byrnes, E. M. (2013). Multigenerational effects of adolescent morphine exposure on dopamine D2 receptor function. Psychopharmacology227(2), 263-272.